7UL4
CryoEM Structure of Inactive MOR Bound to Alvimopan and Mb6
Summary for 7UL4
Entry DOI | 10.2210/pdb7ul4/pdb |
EMDB information | 26591 |
Descriptor | Mu-type opioid receptor, Megabody 6, N-[(2S)-2-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]methyl}-3-phenylpropanoyl]glycine, ... (4 entities in total) |
Functional Keywords | antagonist, complex, membrane protein |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 104007.35 |
Authors | Robertson, M.J.,Skiniotis, G. (deposition date: 2022-04-03, release date: 2022-06-29, Last modification date: 2022-12-28) |
Primary citation | Robertson, M.J.,Papasergi-Scott, M.M.,He, F.,Seven, A.B.,Meyerowitz, J.G.,Panova, O.,Peroto, M.C.,Che, T.,Skiniotis, G. Structure determination of inactive-state GPCRs with a universal nanobody. Nat.Struct.Mol.Biol., 29:1188-1195, 2022 Cited by PubMed: 36396979DOI: 10.1038/s41594-022-00859-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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