7UGI
Bromodomain of EP300 liganded with BMS-536924
Summary for 7UGI
Entry DOI | 10.2210/pdb7ugi/pdb |
Descriptor | Histone acetyltransferase p300, (3M)-4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-3-[4-methyl-6-(morpholin-4-yl)-1H-benzimidazol-2-yl]pyridin-2(1H)-one, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ... (5 entities in total) |
Functional Keywords | bromodomain, small molecule ligand, complex, transcription |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 29570.61 |
Authors | Schonbrunn, E.,Bikowitz, M. (deposition date: 2022-03-24, release date: 2023-04-12, Last modification date: 2023-10-25) |
Primary citation | Schonbrunn, E.,Bikowitz, M. Structural basis of CBP and EP300 interaction with kinase inhibitors To Be Published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)