7UGI
Bromodomain of EP300 liganded with BMS-536924
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Histone acetyltransferase p300 | polymer | 116 | 13826.8 | 2 | UniProt (Q09472) Pfam (PF00439) In PDB | Homo sapiens (human) | p300 HAT,E1A-associated protein p300,Histone butyryltransferase p300,Histone crotonyltransferase p300,Protein 2-hydroxyisobutyryltransferase p300,Protein lactyltransferas p300,Protein propionyltransferase p300 |
| 2 | A, B | (3M)-4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-3-[4-methyl-6-(morpholin-4-yl)-1H-benzimidazol-2-yl]pyridin-2(1H)-one | non-polymer | 480.0 | 2 | Chemie (N6I) | |||
| 3 | A | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL | non-polymer | 398.5 | 1 | Chemie (PE5) | |||
| 4 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
| 5 | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A, B: 1048 - 1161 (UniProt: Q09472)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Met -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27653.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1917.0 | |
| All* | Total formula weight | 29570.6 |
