7UAI

Meprin alpha helix in complex with fetuin-B

7UAI の概要

• エントリーDOI: 10.2210/pdb7uai/pdb
• EMDBエントリー: 26419 26420 26421 26422 26423 26424 26426
• 分子名称: Meprin A subunit alpha, Fetuin-B, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: metalloprotease, complex, helical, extracellular, oncoprotein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 364672.47

構造登録者

Bayly-Jones, C.,Lupton, C.J.,Fritz, C.,Schlenzig, D.,Whisstock, J.C. (登録日: 2022-03-13, 公開日: 2022-11-02)

• 主引用文献: Bayly-Jones, C.,Lupton, C.J.,Fritz, C.,Venugopal, H.,Ramsbeck, D.,Wermann, M.,Jager, C.,de Marco, A.,Schilling, S.,Schlenzig, D.,Whisstock, J.C.; Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor.; Nat Commun, 13:6178-6178, 2022; PubMed: 36261433; DOI: 10.1038/s41467-022-33893-7

実験手法

ELECTRON MICROSCOPY (2.8 Å)