7U8Y

TREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics

7U8Y の概要

• エントリーDOI: 10.2210/pdb7u8y/pdb
• 分子名称: Three-prime repair exonuclease 1, ALIZARIN RED, MANGANESE (II) ION, ... (4 entities in total)
• 機能のキーワード: inhibitor, exonuclease, immunotherapy, complex, dna binding protein, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Mus musculus (house mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 51678.12

構造登録者

Hemphill, W.O.,Harvey, S.E.,Simpson, S.R.,Smalley, T.L.,Salsbury, F.R.,Perrino, F.W.,Hollis, T. (登録日: 2022-03-09, 公開日: 2023-03-15, 最終更新日: 2023-10-25)

• 主引用文献: Hemphill, W.O.,Harvey, S.E.,Simpson, S.R.,Smalley, T.L.,Salsbury, F.R.,Perrino, F.W.,Hollis, T.; TREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics; to be published,

実験手法

X-RAY DIFFRACTION (2.22 Å)