7TXH
Human MRas Q71R in complex with human Shoc2 LRR domain M173I and human PP1Ca
Summary for 7TXH
Entry DOI | 10.2210/pdb7txh/pdb |
Descriptor | Ras-related protein M-Ras, Leucine-rich repeat protein SHOC-2, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, ... (9 entities in total) |
Functional Keywords | ras, pp1, shoc2, lrr, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 225667.97 |
Authors | Hauseman, Z.J.,Viscomi, J.,Dhembi, A.,Clark, K.,King, D.A.,Fodor, M. (deposition date: 2022-02-09, release date: 2022-06-22, Last modification date: 2023-10-18) |
Primary citation | Hauseman, Z.J.,Fodor, M.,Dhembi, A.,Viscomi, J.,Egli, D.,Bleu, M.,Katz, S.,Park, E.,Jang, D.M.,Porter, K.A.,Meili, F.,Guo, H.,Kerr, G.,Molle, S.,Velez-Vega, C.,Beyer, K.S.,Galli, G.G.,Maira, S.M.,Stams, T.,Clark, K.,Eck, M.J.,Tordella, L.,Thoma, C.R.,King, D.A. Structure of the MRAS-SHOC2-PP1C phosphatase complex. Nature, 609:416-423, 2022 Cited by PubMed: 35830882DOI: 10.1038/s41586-022-05086-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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