7TWN

Crystal structure of SARS-CoV-2 NSP3 macrodomain at pH 5 (P43 crystal form)

Summary for 7TWN

Entry DOI	10.2210/pdb7twn/pdb
Descriptor	Non-structural protein 3, CITRIC ACID, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... (4 entities in total)
Functional Keywords	sars-cov-2, room temperature diffraction, protein dynamics, water networks, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2
Total number of polymer chains	2
Total formula weight	36949.07
Authors	Correy, G.J.,Fraser, J.S. (deposition date: 2022-02-07, release date: 2022-02-23, Last modification date: 2023-10-18)
Primary citation	Correy, G.J.,Kneller, D.W.,Phillips, G.,Pant, S.,Russi, S.,Cohen, A.E.,Meigs, G.,Holton, J.M.,Gahbauer, S.,Thompson, M.C.,Ashworth, A.,Coates, L.,Kovalevsky, A.,Meilleur, F.,Fraser, J.S. The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature. Sci Adv, 8:eabo5083-eabo5083, 2022 Cited by PubMed: 35622909 DOI: 10.1126/sciadv.abo5083 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (0.9 Å)

Structure validation