7TUF
Crystal structure of Tapasin in complex with PaSta1-Fab
Summary for 7TUF
Entry DOI | 10.2210/pdb7tuf/pdb |
Related | 7TUC 7TUD 7TUE 7TUG 7TUH |
Descriptor | Tapasin, PaSta1 Fab heavy chain, PaSta1 Fab kappa light chain, ... (5 entities in total) |
Functional Keywords | pasta, fab, antibody, igg, mhc-i, hla, peptide loading complex, plc, antigen presentation, immune response, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 187453.92 |
Authors | Jiang, J.,Natarajan, K.,Taylor, D.K.,Boyd, L.F.,Margulies, D.H. (deposition date: 2022-02-02, release date: 2022-09-07, Last modification date: 2023-10-18) |
Primary citation | Jiang, J.,Taylor, D.K.,Kim, E.J.,Boyd, L.F.,Ahmad, J.,Mage, M.G.,Truong, H.V.,Woodward, C.H.,Sgourakis, N.G.,Cresswell, P.,Margulies, D.H.,Natarajan, K. Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. Nat Commun, 13:5470-5470, 2022 Cited by PubMed: 36115831DOI: 10.1038/s41467-022-33153-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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