7TTZ

Heterodimeric IgA Fc in complex with Staphylococcus aureus protein SSL7

7TTZ の概要

• エントリーDOI: 10.2210/pdb7ttz/pdb
• 分子名称: IgA Fc, Superantigen-like protein SSL7, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: iga, heterodimer, antibody fc, antibody engineering, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 96213.00

構造登録者

Boulanger, M.J.,Verstraete, M.,Heinkel, F.,Escobar, E.,Dixit, S.,Von Kreudenstein, T.S. (登録日: 2022-02-02, 公開日: 2023-02-01, 最終更新日: 2023-10-25)

• 主引用文献: Heinkel, F.,Verstraete, M.M.,Cao, S.,Li, J.,Farber, P.,Stangle, E.,Silva-Moreno, B.,Peng, F.,Dixit, S.,Boulanger, M.J.,Spreter Von Kreudenstein, T.,Escobar-Cabrera, E.; Engineering a pure and stable heterodimeric IgA for the development of multispecific therapeutics.; Mabs, 14:2141637-2141637, 2022; PubMed: 36343329; DOI: 10.1080/19420862.2022.2141637

実験手法

X-RAY DIFFRACTION (2.35 Å)