7TJ2
SARS-CoV-2 endoribonuclease Nsp15 bound to dsRNA
Summary for 7TJ2
Entry DOI | 10.2210/pdb7tj2/pdb |
EMDB information | 25915 |
Descriptor | Uridylate-specific endoribonuclease nsp15, RNA (31-MER) (3 entities in total) |
Functional Keywords | endoribonuclease, viral protein, viral protein-rna complex, viral protein/rna |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 8 |
Total formula weight | 268789.89 |
Authors | Frazier, M.N.,Krahn, J.M.,Butay, K.J.,Dillard, L.B.,Borgnia, M.J.,Stanley, R.E. (deposition date: 2022-01-14, release date: 2022-03-23, Last modification date: 2024-06-05) |
Primary citation | Frazier, M.N.,Wilson, I.M.,Krahn, J.M.,Butay, K.J.,Dillard, L.B.,Borgnia, M.J.,Stanley, R.E. Flipped over U: structural basis for dsRNA cleavage by the SARS-CoV-2 endoribonuclease. Nucleic Acids Res., 50:8290-8301, 2022 Cited by PubMed: 35801916DOI: 10.1093/nar/gkac589 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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