7TJ2
SARS-CoV-2 endoribonuclease Nsp15 bound to dsRNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Uridylate-specific endoribonuclease nsp15 | polymer | 350 | 39246.7 | 6 | UniProt (P0DTD1) Pfam (PF19219) Pfam (PF19216) Pfam (PF19215) In PDB | Severe acute respiratory syndrome coronavirus 2 | NendoU,Non-structural protein 15,nsp15 |
| 2 | G | RNA (31-MER) | polymer | 52 | 16781.0 | 1 | synthetic construct | ||
| 3 | H | RNA (31-MER) | polymer | 52 | 16528.8 | 1 | synthetic construct |
Sequence modifications
A, B, C, D, E, F: 2 - 347 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Glu 0 | - | expression tag |
| Met 1 | - | expression tag |
| Ala 235 | His 6686 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 268789.9 | |
| All* | Total formula weight | 268789.9 |
