7TE6
Crystal structure of GluN1b-2B ATD complexed to Fab5 anti-GluN2B antibody
Summary for 7TE6
Entry DOI | 10.2210/pdb7te6/pdb |
Descriptor | Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2B, Fab5 heavy chain, ... (4 entities in total) |
Functional Keywords | fab fragment complexed to the receptor, signaling protein-immune system complex, signaling protein/immune system |
Biological source | Xenopus laevis (African clawed frog) More |
Total number of polymer chains | 8 |
Total formula weight | 263999.79 |
Authors | Regan, M.,Tajima, N.,Furukawa, H. (deposition date: 2022-01-04, release date: 2022-03-02, Last modification date: 2023-10-18) |
Primary citation | Tajima, N.,Simorowski, N.,Yovanno, R.A.,Regan, M.C.,Michalski, K.,Gomez, R.,Lau, A.Y.,Furukawa, H. Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13:923-923, 2022 Cited by PubMed: 35177668DOI: 10.1038/s41467-022-28559-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.55 Å) |
Structure validation
Download full validation report