7TD5
Structure of human PRC2-EZH1 containing phosphorylated SUZ12
Summary for 7TD5
Entry DOI | 10.2210/pdb7td5/pdb |
Descriptor | Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, Polycomb protein SUZ12, ... (7 entities in total) |
Functional Keywords | transcription regulatory complex, histone modification, transcription |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 10 |
Total formula weight | 304787.73 |
Authors | |
Primary citation | Gong, L.,Liu, X.,Jiao, L.,Yang, X.,Lemoff, A.,Liu, X. CK2-mediated phosphorylation of SUZ12 promotes PRC2 function by stabilizing enzyme active site. Nat Commun, 13:6781-6781, 2022 Cited by PubMed: 36351927DOI: 10.1038/s41467-022-34431-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.994 Å) |
Structure validation
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