7TD5

Structure of human PRC2-EZH1 containing phosphorylated SUZ12

7TD5 の概要

• エントリーDOI: 10.2210/pdb7td5/pdb
• 分子名称: Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, Polycomb protein SUZ12, ... (7 entities in total)
• 機能のキーワード: transcription regulatory complex, histone modification, transcription
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 304787.73

構造登録者

Gong, L.,Jiao, L.,Liu, X. (登録日: 2021-12-30, 公開日: 2022-11-16, 最終更新日: 2023-10-18)

• 主引用文献: Gong, L.,Liu, X.,Jiao, L.,Yang, X.,Lemoff, A.,Liu, X.; CK2-mediated phosphorylation of SUZ12 promotes PRC2 function by stabilizing enzyme active site.; Nat Commun, 13:6781-6781, 2022; PubMed: 36351927; DOI: 10.1038/s41467-022-34431-1

実験手法

X-RAY DIFFRACTION (2.994 Å)