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7T9A

ApexGT2 in complex with GT2-d42.16 and RM20A3 Fabs

This is a non-PDB format compatible entry.
Summary for 7T9A
Entry DOI10.2210/pdb7t9a/pdb
EMDB information25754
DescriptorHIV Envelope ApexGT2 gp120, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
Functional Keywordshiv, germline targeting, vaccine, viral protein, viral protein-immune system complex, viral protein/immune system
Biological sourceHuman immunodeficiency virus 1
More
Total number of polymer chains14
Total formula weight341446.98
Authors
Berndsen, Z.T.,Ward, A.B. (deposition date: 2021-12-18, release date: 2022-09-28, Last modification date: 2024-10-30)
Primary citationMelzi, E.,Willis, J.,Ma, K.,Lin, Y.,Kratochvil, S.,Berndsen, Z.T.,Nair, U.,Warner, J.,Steichen, J.,Pecetta, S.,Perez, M.,Kirsch, K.,Ward, A.B.,Schief, W.,Batista, F.D.
Priming HIV Envelope V2 Apex-directed broadly neutralizing antibody responses with protein or mRNA immunogens
Immunity, 2022
Experimental method
ELECTRON MICROSCOPY (3.54 Å)
Structure validation

227344

數據於2024-11-13公開中

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