7T8W
Structure of antibody 3G12 bound to Respiratory Syncytial Virus G central conserved domain mutant S177Q
Summary for 7T8W
Entry DOI | 10.2210/pdb7t8w/pdb |
Descriptor | 3G12 Fab Light chain, 3G12 Fab Heavy chain, Mature secreted glycoprotein G (3 entities in total) |
Functional Keywords | respiratory syncytial virus, human antibody, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 53834.27 |
Authors | Nunez Castrejon, A.M.,O'Rourke, S.M.,Kauvar, L.M.,DuBois, R.M. (deposition date: 2021-12-17, release date: 2022-02-09, Last modification date: 2023-10-18) |
Primary citation | Nunez Castrejon, A.M.,O'Rourke, S.M.,Kauvar, L.M.,DuBois, R.M. Structure-Based Design and Antigenic Validation of Respiratory Syncytial Virus G Immunogens. J.Virol., 96:e0220121-e0220121, 2022 Cited by PubMed: 35266806DOI: 10.1128/jvi.02201-21 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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