7T8W

Structure of antibody 3G12 bound to Respiratory Syncytial Virus G central conserved domain mutant S177Q

7T8W の概要

• エントリーDOI: 10.2210/pdb7t8w/pdb
• 分子名称: 3G12 Fab Light chain, 3G12 Fab Heavy chain, Mature secreted glycoprotein G (3 entities in total)
• 機能のキーワード: respiratory syncytial virus, human antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 53834.27

構造登録者

Nunez Castrejon, A.M.,O'Rourke, S.M.,Kauvar, L.M.,DuBois, R.M. (登録日: 2021-12-17, 公開日: 2022-02-09, 最終更新日: 2023-10-18)

• 主引用文献: Nunez Castrejon, A.M.,O'Rourke, S.M.,Kauvar, L.M.,DuBois, R.M.; Structure-Based Design and Antigenic Validation of Respiratory Syncytial Virus G Immunogens.; J.Virol., 96:e0220121-e0220121, 2022; PubMed: 35266806; DOI: 10.1128/jvi.02201-21

実験手法

X-RAY DIFFRACTION (3.1 Å)