7T6I

Crystal structure of HLA-DP1 in complex with pp65 peptide in reverse orientation

Summary for 7T6I

• Entry DOI: 10.2210/pdb7t6i/pdb
• Descriptor: HLA class II histocompatibility antigen DP alpha chain, MHC class II antigen, pp65 peptide, ... (7 entities in total)
• Functional Keywords: antigen presentation, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 45847.97

Authors

Lim, J.J.,Reid, H.,Rossjohn, J. (deposition date: 2021-12-13, release date: 2022-12-07, Last modification date: 2023-10-25)

• Primary citation: Klobuch, S.,Lim, J.J.,van Balen, P.,Kester, M.G.D.,de Klerk, W.,de Ru, A.H.,Pothast, C.R.,Jedema, I.,Drijfhout, J.W.,Rossjohn, J.,Reid, H.H.,van Veelen, P.A.,Falkenburg, J.H.F.,Heemskerk, M.H.M.; Human T cells recognize HLA-DP-bound peptides in two orientations.; Proc.Natl.Acad.Sci.USA, 119:e2214331119-e2214331119, 2022; PubMed: 36442096; DOI: 10.1073/pnas.2214331119

Experimental method

X-RAY DIFFRACTION (2.3 Å)