7T6I

Crystal structure of HLA-DP1 in complex with pp65 peptide in reverse orientation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	HLA class II histocompatibility antigen DP alpha chain	polymer	183	21020.3	1	UniProt (Q95HB9) Pfam (PF00993) Pfam (PF07654) In PDB	Homo sapiens (human)	HLA-DPA1 protein,HLA-DPA1*02:01:01:NEW,MHC class II antigen
2	B	MHC class II antigen	polymer	191	22173.7	1	UniProt (S6B6U4) Pfam (PF00969) Pfam (PF07654) In PDB	Homo sapiens (human)
3	C	pp65 peptide	polymer	17	1853.1	1	UniProt (P06725) In PDB	Human cytomegalovirus (strain AD169)	pp65,65 kDa matrix phosphoprotein,Phosphoprotein UL83,Tegument protein UL83
4	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
5	A	GLYCINE	non-polymer		75.1	1	Chemie (GLY)
6	B	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
7		water	water		18.0	191	Chemie (HOH)

Sequence modifications

A: 1 - 180 (UniProt: Q95HB9)

PDB	External Database	Details
Thr 181	-	expression tag
Ser 182	-	expression tag
Gly 183	-	expression tag

B: 1 - 188 (UniProt: S6B6U4)

PDB	External Database	Details
Thr 189	-	expression tag
Gly 190	-	expression tag
Gly 191	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	45047.2
Non-Polymers*	Number of molecules	5
	Total formula weight	800.8
All*	Total formula weight	45848.0

*Water molecules are not included.