7T6B

Structure of S1PR2-heterotrimeric G13 signaling complex

7T6B の概要

• エントリーDOI: 10.2210/pdb7t6b/pdb
• EMDBエントリー: 25712
• 分子名称: Guanine nucleotide-binding protein subunit alpha-13, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• 機能のキーワード: s1p, s1pr2, gpcr, membrane protein, cryo-em, signaling protein-immune system complex, signaling protein/immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 158154.27

構造登録者

Li, X.,Chen, H. (登録日: 2021-12-13, 公開日: 2022-04-06, 最終更新日: 2022-06-29)

• 主引用文献: Chen, H.,Chen, K.,Huang, W.,Staudt, L.M.,Cyster, J.G.,Li, X.; Structure of S1PR2-heterotrimeric G 13 signaling complex.; Sci Adv, 8:eabn0067-eabn0067, 2022; PubMed: 35353559; DOI: 10.1126/sciadv.abn0067

実験手法

ELECTRON MICROSCOPY (3.19 Å)