7T37
Activated state of 2-APB and CBD-bound wildtype rat TRPV2 in nanodiscs
Summary for 7T37
Entry DOI | 10.2210/pdb7t37/pdb |
EMDB information | 25650 25651 |
Descriptor | Transient receptor potential cation channel subfamily V member 2, cannabidiol, 2-aminoethyl diphenylborinate (3 entities in total) |
Functional Keywords | trp channel, ion channel, trpv, transport protein |
Biological source | Rattus norvegicus (Norway rat) |
Total number of polymer chains | 4 |
Total formula weight | 349353.79 |
Authors | Pumroy, R.A.,Protopopova, A.D.,Gallo, P.N.,Moiseenkova-Bell, V.Y. (deposition date: 2021-12-07, release date: 2022-05-04, Last modification date: 2024-02-28) |
Primary citation | Pumroy, R.A.,Protopopova, A.D.,Fricke, T.C.,Lange, I.U.,Haug, F.M.,Nguyen, P.T.,Gallo, P.N.,Sousa, B.B.,Bernardes, G.J.L.,Yarov-Yarovoy, V.,Leffler, A.,Moiseenkova-Bell, V.Y. Structural insights into TRPV2 activation by small molecules. Nat Commun, 13:2334-2334, 2022 Cited by PubMed: 35484159DOI: 10.1038/s41467-022-30083-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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