7T2T

SARS-CoV2 Mpro native form

Summary for 7T2T

Entry DOI	10.2210/pdb7t2t/pdb
Descriptor	3C-like proteinase (2 entities in total)
Functional Keywords	sars-cov2, 3c-like protease, mpro, 2clpro, hydrolase
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
Total number of polymer chains	1
Total formula weight	33825.55
Authors	Mathews, I.I.,Hameedi, M.A.,Wakatsuki, S. (deposition date: 2021-12-06, release date: 2022-09-14, Last modification date: 2023-10-18)
Primary citation	Hameedi, M.A.,T Prates, E.,Garvin, M.R.,Mathews, I.I.,Amos, B.K.,Demerdash, O.,Bechthold, M.,Iyer, M.,Rahighi, S.,Kneller, D.W.,Kovalevsky, A.,Irle, S.,Vuong, V.Q.,Mitchell, J.C.,Labbe, A.,Galanie, S.,Wakatsuki, S.,Jacobson, D. Structural and functional characterization of NEMO cleavage by SARS-CoV-2 3CLpro. Nat Commun, 13:5285-5285, 2022 Cited by PubMed: 36075915 DOI: 10.1038/s41467-022-32922-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation