7T2I
Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-588
Summary for 7T2I
Entry DOI | 10.2210/pdb7t2i/pdb |
Descriptor | Transcription initiation factor TFIID subunit 1, DIMETHYL SULFOXIDE, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | bromodomain, taf1, tata binding protein, tbp, tandem bromodomain, protac, degrader, bifunctional degrader, gene regulation |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 31645.10 |
Authors | Karim, M.R.,Schonbrunn, E. (deposition date: 2021-12-04, release date: 2022-01-19, Last modification date: 2023-10-18) |
Primary citation | Karim, M.R.,Schonbrunn, E. Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-588 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.89 Å) |
Structure validation
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