7T2I

Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-588

Summary for 7T2I

• Entry DOI: 10.2210/pdb7t2i/pdb
• Descriptor: Transcription initiation factor TFIID subunit 1, DIMETHYL SULFOXIDE, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: bromodomain, taf1, tata binding protein, tbp, tandem bromodomain, protac, degrader, bifunctional degrader, gene regulation
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 31645.10

Authors

Karim, M.R.,Schonbrunn, E. (deposition date: 2021-12-04, release date: 2022-01-19, Last modification date: 2023-10-18)

• Primary citation: Karim, M.R.,Schonbrunn, E.; Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-588; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.89 Å)