7T2I
Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-588
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Transcription initiation factor TFIID subunit 1 | polymer | 265 | 30968.3 | 1 | UniProt (P21675) Pfam (PF00439) In PDB | Homo sapiens (human) | Cell cycle gene 1 protein,TBP-associated factor 250 kDa,p250,Transcription initiation factor TFIID 250 kDa subunit,TAFII250 |
| 2 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | A | 4-(6-{1-[(R)-S-methanesulfonimidoyl]cyclopropyl}-2-[(3R)-3-methylmorpholin-4-yl]pyrimidin-4-yl)-1H-pyrrolo[2,3-b]pyridine | non-polymer | 412.5 | 1 | Chemie (E9F) | |||
| 5 | water | water | 18.0 | 252 | Chemie (HOH) |
Sequence modifications
A: 1373 - 1635 (UniProt: P21675)
| PDB | External Database | Details |
|---|---|---|
| Ser 1371 | - | expression tag |
| Met 1372 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30968.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 676.8 | |
| All* | Total formula weight | 31645.1 |
