7T10

CryoEM structure of somatostatin receptor 2 in complex with somatostatin-14 and Gi3

Summary for 7T10

Entry DOI	10.2210/pdb7t10/pdb
EMDB information	25586
Descriptor	Somatostatin receptor type 2,Kappa-type opioid receptor, Guanine nucleotide-binding protein G(i) subunit alpha-3, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total)
Functional Keywords	gpcr, receptor, complex, membrane protein, membrane protein-signaling protein complex, membrane protein/signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	161327.42
Authors	Robertson, M.J.,Skinotis, G. (deposition date: 2021-11-30, release date: 2022-03-09, Last modification date: 2022-03-30)
Primary citation	Robertson, M.J.,Meyerowitz, J.G.,Panova, O.,Borrelli, K.,Skiniotis, G. Plasticity in ligand recognition at somatostatin receptors. Nat.Struct.Mol.Biol., 29:210-217, 2022 Cited by PubMed: 35210615 DOI: 10.1038/s41594-022-00727-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.5 Å)

Structure validation