7T0T

Crystal structure of the BCL6 BTB domain in complex with OICR-10562

Summary for 7T0T

• Entry DOI: 10.2210/pdb7t0t/pdb
• Related: 7LWE 7LWF 7LWG 7LZQ 7LZS 7RUW 7RUX 7RUY 7RUZ 7RV0 7RV1 7RV2 7RV3 7RV4 7RV5 7RV6 7RV7 7RV8 7RV9
• Descriptor: Isoform 2 of B-cell lymphoma 6 protein, DIMETHYL SULFOXIDE, N-[5-chloro-2-(morpholin-4-yl)pyridin-4-yl]-2-[5-(3-cyano-4-hydroxy-5-methylphenyl)-3-methyl-2-(1-methyl-1H-pyrazol-4-yl)-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl]acetamide, ... (4 entities in total)
• Functional Keywords: immunity, inflammatory response, transcription repressor, transcription-transcription inhibitor complex, transcription/transcription inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 91199.53

Authors

Kuntz, D.A.,Prive, G.G. (deposition date: 2021-11-30, release date: 2022-12-14, Last modification date: 2023-10-25)

• Primary citation: Kuntz, D.A.,Prive, G.G.; Crystal structure of the BCL6 BTB domain in complex with OICR-10562; To Be Published,

Experimental method