7SUV

APE1 exonuclease substrate complex with 8oxoG opposite A

Summary for 7SUV

• Entry DOI: 10.2210/pdb7suv/pdb
• Descriptor: DNA (5'-D(P*TP*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(8OG))-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*AP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... (5 entities in total)
• Functional Keywords: nuclease, dna repair protein, dna binding protein, hydrolase, hydrolase-dna complex, hydrolase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 75193.38

Authors

Whitaker, A.W.,Freudenthal, B.D. (deposition date: 2021-11-18, release date: 2022-09-07, Last modification date: 2023-10-18)

• Primary citation: Whitaker, A.M.,Stark, W.J.,Freudenthal, B.D.; Processing oxidatively damaged bases at DNA strand breaks by APE1.; Nucleic Acids Res., 50:9521-9533, 2022; PubMed: 36018803; DOI: 10.1093/nar/gkac695

Experimental method

X-RAY DIFFRACTION (1.99 Å)