7ST3
Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity
This is a non-PDB format compatible entry.
Summary for 7ST3
| Entry DOI | 10.2210/pdb7st3/pdb |
| Descriptor | Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH (3 entities in total) |
| Functional Keywords | hla, vhh, sct, hpv, immune system-viral protein complex, immune system/viral protein |
| Biological source | Human papillomavirus type 16 More |
| Total number of polymer chains | 32 |
| Total formula weight | 973054.34 |
| Authors | Finton, K.A.K.,Rupert, P.B. (deposition date: 2021-11-11, release date: 2022-11-23, Last modification date: 2023-10-25) |
| Primary citation | Finton, K.A.K.,Rupert, P.B.,Friend, D.J.,Dinca, A.,Lovelace, E.S.,Buerger, M.,Rusnac, D.V.,Foote-McNabb, U.,Chour, W.,Heath, J.R.,Campbell, J.S.,Pierce, R.H.,Strong, R.K. Effects of HLA single chain trimer design on peptide presentation and stability. Front Immunol, 14:1170462-1170462, 2023 Cited by PubMed: 37207206DOI: 10.3389/fimmu.2023.1170462 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.78 Å) |
Structure validation
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