7SO5

Novel structural insights for a pair of monoclonal antibodies recognizing non-overlapping epitopes of the glucosyltransferase domain of Clostridium difficile toxin B

7SO5 の概要

• エントリーDOI: 10.2210/pdb7so5/pdb
• 分子名称: Fab B2 HC, Fab B2 LC, Toxin B, ... (4 entities in total)
• 機能のキーワード: antibody, toxin, tcdb, epitope, clostridium difficile toxin, toxin-immune system complex, toxin/immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 109366.44

構造登録者

Liu, J. (登録日: 2021-10-29, 公開日: 2022-05-11, 最終更新日: 2023-10-18)

• 主引用文献: Liu, J.,Kothe, M.,Zhang, J.,Oloo, E.,Stegalkina, S.,Mundle, S.T.,Li, L.,Zhang, J.,Cole, L.E.,Barone, L.,Biemann, H.P.,Kleanthous, H.,Anosova, N.G.,Anderson, S.F.; Novel structural insights for a pair of monoclonal antibodies recognizing non-overlapping epitopes of the glucosyltransferase domain of Clostridium difficile toxin B.; Curr Res Struct Biol, 4:96-105, 2022; PubMed: 35469152; DOI: 10.1016/j.crstbi.2022.03.003

実験手法

X-RAY DIFFRACTION (1.797 Å)