7SNI

Structure of G6PD-D200N tetramer bound to NADP+ and G6P

Summary for 7SNI

Entry DOI	10.2210/pdb7sni/pdb
EMDB information	25227
Descriptor	Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 6-O-phosphono-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	d200n mutant, oxidoreductase
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	248598.83
Authors	Wei, X.,Marmorstein, R. (deposition date: 2021-10-28, release date: 2022-07-13, Last modification date: 2022-08-03)
Primary citation	Wei, X.,Kixmoeller, K.,Baltrusaitis, E.,Yang, X.,Marmorstein, R. Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity. Proc.Natl.Acad.Sci.USA, 119:e2119695119-e2119695119, 2022 Cited by PubMed: 35858355 DOI: 10.1073/pnas.2119695119 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.5 Å)

Structure validation