7SI5

CRYSTAL STRUCTURE OF EED WITH MRTX-1919

Summary for 7SI5

• Entry DOI: 10.2210/pdb7si5/pdb
• Related: 7SI4
• Descriptor: Polycomb protein EED, SODIUM ION, (4R)-8-(1,3-dimethyl-1H-pyrazol-5-yl)-5-{[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]amino}imidazo[1,2-c]pyrimidine-2-carbonitrile, ... (6 entities in total)
• Functional Keywords: eed, oncology, transcription-transferase, gene regulation
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 47330.20

Authors

Gunn, R.J.,Burns, A.C.,Lawson, J.D.,Marx, M.A. (deposition date: 2021-10-12, release date: 2022-11-09, Last modification date: 2024-04-03)

• Primary citation: Burns, A.C.; CRYSTAL STRUCTURE OF EED WITH MRTX-1919; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (1.75 Å)