7SI5
CRYSTAL STRUCTURE OF EED WITH MRTX-1919
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Polycomb protein EED | polymer | 402 | 46158.3 | 1 | UniProt (O75530) Pfam (PF00400) | Homo sapiens (Human) | hEED,Embryonic ectoderm development protein,WD protein associating with integrin cytoplasmic tails 1,WAIT-1 |
| 2 | B, C (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 3 | D (A) | (4R)-8-(1,3-dimethyl-1H-pyrazol-5-yl)-5-{[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]amino}imidazo[1,2-c]pyrimidine-2-carbonitrile | non-polymer | 403.4 | 1 | Chemie (9L0) | |||
| 4 | E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | G, H, I, J, K... (A) | FORMIC ACID | non-polymer | 46.0 | 13 | Chemie (FMT) | |||
| 6 | T (A) | water | water | 18.0 | 369 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 46158.3 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 1171.9 | |
| All* | Total formula weight | 47330.2 |
