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7SI5

CRYSTAL STRUCTURE OF EED WITH MRTX-1919

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APolycomb protein EEDpolymer40246158.31UniProt (O75530)
Pfam (PF00400)
In PDB
Homo sapiens (Human)hEED,Embryonic ectoderm development protein,WD protein associating with integrin cytoplasmic tails 1,WAIT-1
2ASODIUM IONnon-polymer23.02Chemie (NA)
3A(4R)-8-(1,3-dimethyl-1H-pyrazol-5-yl)-5-{[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]amino}imidazo[1,2-c]pyrimidine-2-carbonitrilenon-polymer403.41Chemie (9L0)
4A1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
5AFORMIC ACIDnon-polymer46.013Chemie (FMT)
6waterwater18.0369Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight46158.3
Non-Polymers*Number of molecules18
Total formula weight1171.9
All*Total formula weight47330.2
*Water molecules are not included.

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PDB entries from 2024-07-10

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