7SI0

IgE-Fc in complex with 813

Summary for 7SI0

• Entry DOI: 10.2210/pdb7si0/pdb
• Related: 7SHT 7SHU 7SHY 7SHZ
• Descriptor: IgE Fc, 813 Variable fragment Heavy chain, 813 Variable fragment Light chain, ... (8 entities in total)
• Functional Keywords: ige, omalizumab, xolair, inhibitor, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 226328.11

Authors

Pennington, L.F.,Jardetzky, T.J.,Kleinboelting, S. (deposition date: 2021-10-12, release date: 2021-12-15, Last modification date: 2023-10-18)

• Primary citation: Pennington, L.F.,Gasser, P.,Kleinboelting, S.,Zhang, C.,Skiniotis, G.,Eggel, A.,Jardetzky, T.S.; Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.; Nat Commun, 12:7069-7069, 2021; PubMed: 34862384; DOI: 10.1038/s41467-021-27397-z

Experimental method

X-RAY DIFFRACTION (3 Å)