7SF4

M. tb EgtD in complex with imatinib

Summary for 7SF4

Entry DOI	10.2210/pdb7sf4/pdb
Descriptor	Histidine N-alpha-methyltransferase, 2-AMINO-4-PYRIDYL-PYRIMIDINE, GLYCEROL, ... (5 entities in total)
Functional Keywords	ergothioneine biosynthesis pathway, rossmann fold domain, histidine binding site, sam dependent methyltransferase, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	72023.06
Authors	Sudasinghe, T.D.,Ronning, D.R. (deposition date: 2021-10-03, release date: 2021-12-01, Last modification date: 2023-10-18)
Primary citation	Sudasinghe, T.D.,Banco, M.T.,Ronning, D.R. Inhibitors of Mycobacterium tuberculosis EgtD target both substrate binding sites to limit hercynine production. Sci Rep, 11:22240-22240, 2021 Cited by PubMed: 34782676 DOI: 10.1038/s41598-021-01526-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.39 Å)

Structure validation