7SCG

FH210 bound Mu Opioid Receptor-Gi Protein Complex

Summary for 7SCG

Entry DOI	10.2210/pdb7scg/pdb
EMDB information	25034
Descriptor	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Mu-type opioid receptor, ... (7 entities in total)
Functional Keywords	gpcr, membrane protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	5
Total formula weight	154101.75
Authors	Wang, H.,Kobilka, B. (deposition date: 2021-09-28, release date: 2022-04-20, Last modification date: 2022-07-06)
Primary citation	Wang, H.,Hetzer, F.,Huang, W.,Qu, Q.,Meyerowitz, J.,Kaindl, J.,Hubner, H.,Skiniotis, G.,Kobilka, B.K.,Gmeiner, P. Structure-Based Evolution of G Protein-Biased mu-Opioid Receptor Agonists. Angew.Chem.Int.Ed.Engl., 61:e202200269-e202200269, 2022 Cited by PubMed: 35385593 DOI: 10.1002/anie.202200269 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation