7SCG

FH210 bound Mu Opioid Receptor-Gi Protein Complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	polymer	344	37671.1	1	UniProt (P62873) Pfam (PF00400) In PDB	Homo sapiens (Human)	Transducin beta chain 1
2	C	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2	polymer	71	7861.1	1	UniProt (P59768) Pfam (PF00631) In PDB	Homo sapiens (Human)	G gamma-I
3	D	Mu-type opioid receptor	polymer	356	39995.1	1	UniProt (P42866) Pfam (PF00001) In PDB	Mus musculus (Mouse)	M-OR-1,MOR-1
4	A	Guanine nucleotide-binding protein G(i) subunit alpha-1	polymer	354	40415.0	1	UniProt (P63096) Pfam (PF00503) In PDB	Homo sapiens (Human)	Adenylate cyclase-inhibiting G alpha protein
5	E	scFv16	polymer	259	27784.9	1		Mus musculus (Mouse)
6	D	(2E)-N-[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-(naphthalen-1-yl)prop-2-enamide	non-polymer		374.5	1	Chemie (8RI)
7		water	water		18.0	2	Chemie (HOH)

Sequence modifications

B: 2 - 340 (UniProt: P62873)

PDB	External Database	Details
Pro -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Ser 0	-	expression tag
Gly 1	-	expression tag

D: 3 - 358 (UniProt: P42866)

PDB	External Database	Details
Glu 46	-	insertion
Asn 47	-	insertion
Leu 48	-	insertion
Tyr 49	-	insertion
Phe 50	-	insertion
Gln 51	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	153727.3
Non-Polymers*	Number of molecules	1
	Total formula weight	374.5
All*	Total formula weight	154101.8

*Water molecules are not included.