7S7B

Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1)

Summary for 7S7B

• Entry DOI: 10.2210/pdb7s7b/pdb
• EMDB information: 24882
• Descriptor: Exosome RNA helicase MTR4, Zinc finger CCHC domain-containing protein 8,Zinc finger CCHC domain-containing protein 8, RNA-binding protein 7, ... (5 entities in total)
• Functional Keywords: helicase, atpase, rna, exosome, rna binding protein, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 423237.96

Authors

Puno, M.R.,Lima, C.D. (deposition date: 2021-09-15, release date: 2022-06-15, Last modification date: 2024-06-05)

• Primary citation: Puno, M.R.,Lima, C.D.; Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.; Cell, 185:2132-2147.e26, 2022; PubMed: 35688134; DOI: 10.1016/j.cell.2022.04.016

Experimental method

ELECTRON MICROSCOPY (4.06 Å)