7S2J

Crystal structure of sulfonamide resistance enzyme Sul2 apoenzyme

Summary for 7S2J

• Entry DOI: 10.2210/pdb7s2j/pdb
• Related: 7S2K
• Descriptor: Sul2, SULFATE ION, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: tim barrel, alpha beta protein, antibiotic resistance, sulfonamides, structural genomics, csgid, center for structural genomics of infectious diseases, niaid, national institute of allergy and infectious diseases, transferase
• Biological source: uncultured bacterium
• Total number of polymer chains: 4
• Total formula weight: 115685.37

Authors

Stogios, P.J.,Skarina, T.,Michalska, K.,Venkatesan, M.,Di Leo, R.,Savchenko, A.,Joachimiak, A.,Satchell, K.J.F.,Center for Structural Biology of Infectious Diseases (CSBID),Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2021-09-03, release date: 2023-05-03, Last modification date: 2023-10-25)

• Primary citation: Venkatesan, M.,Fruci, M.,Verellen, L.A.,Skarina, T.,Mesa, N.,Flick, R.,Pham, C.,Mahadevan, R.,Stogios, P.J.,Savchenko, A.; Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics.; Nat Commun, 14:4031-4031, 2023; PubMed: 37419898; DOI: 10.1038/s41467-023-39778-7

Experimental method

X-RAY DIFFRACTION (1.85 Å)