7S2J

Crystal structure of sulfonamide resistance enzyme Sul2 apoenzyme

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004156	molecular_function	dihydropteroate synthase activity
A	0005829	cellular_component	cytosol
A	0009396	biological_process	folic acid-containing compound biosynthetic process
A	0016740	molecular_function	transferase activity
A	0042558	biological_process	pteridine-containing compound metabolic process
A	0044237	biological_process	cellular metabolic process
A	0046654	biological_process	tetrahydrofolate biosynthetic process
A	0046656	biological_process	folic acid biosynthetic process
A	0046677	biological_process	response to antibiotic
A	0046872	molecular_function	metal ion binding
B	0004156	molecular_function	dihydropteroate synthase activity
B	0005829	cellular_component	cytosol
B	0009396	biological_process	folic acid-containing compound biosynthetic process
B	0016740	molecular_function	transferase activity
B	0042558	biological_process	pteridine-containing compound metabolic process
B	0044237	biological_process	cellular metabolic process
B	0046654	biological_process	tetrahydrofolate biosynthetic process
B	0046656	biological_process	folic acid biosynthetic process
B	0046677	biological_process	response to antibiotic
B	0046872	molecular_function	metal ion binding
C	0004156	molecular_function	dihydropteroate synthase activity
C	0005829	cellular_component	cytosol
C	0009396	biological_process	folic acid-containing compound biosynthetic process
C	0016740	molecular_function	transferase activity
C	0042558	biological_process	pteridine-containing compound metabolic process
C	0044237	biological_process	cellular metabolic process
C	0046654	biological_process	tetrahydrofolate biosynthetic process
C	0046656	biological_process	folic acid biosynthetic process
C	0046677	biological_process	response to antibiotic
C	0046872	molecular_function	metal ion binding
D	0004156	molecular_function	dihydropteroate synthase activity
D	0005829	cellular_component	cytosol
D	0009396	biological_process	folic acid-containing compound biosynthetic process
D	0016740	molecular_function	transferase activity
D	0042558	biological_process	pteridine-containing compound metabolic process
D	0044237	biological_process	cellular metabolic process
D	0046654	biological_process	tetrahydrofolate biosynthetic process
D	0046656	biological_process	folic acid biosynthetic process
D	0046677	biological_process	response to antibiotic
D	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00792
Number of Residues	16
Details	DHPS_1 Dihydropteroate synthase signature 1. IfGIVNiTsDSFsDgG

Chain	Residue	Details
A	ILE7-GLY22

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site_id	PS00793
Number of Residues	14
Details	DHPS_2 Dihydropteroate synthase signature 2. GAdVIDLGPasSnP

Chain	Residue	Details
A	GLY41-PRO54

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P9WND1

Chain	Residue	Details
A	ASN12
B	ASN12
C	ASN12
D	ASN12

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site_id	SWS_FT_FI2
Number of Residues	20
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P0AC13

Chain	Residue	Details
A	ASP85
B	ARG247
C	ASP85
C	ASN104
C	ASP174
C	LYS213
C	ARG247
D	ASP85
D	ASN104
D	ASP174
D	LYS213
A	ASN104
D	ARG247
A	ASP174
A	LYS213
A	ARG247
B	ASP85
B	ASN104
B	ASP174
B	LYS213

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