Summary for 7RY7
Entry DOI | 10.2210/pdb7ry7/pdb |
Descriptor | Plasmepsin X, 2-acetamido-2-deoxy-beta-D-glucopyranose, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | ssgcid, plasmepsin x, plasmodium falciparum, pm10, pmx, structural genomics, seattle structural genomics center for infectious disease, hydrolase |
Biological source | Plasmodium falciparum (isolate 3D7) |
Total number of polymer chains | 1 |
Total formula weight | 53364.27 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2021-08-24, release date: 2022-02-02, Last modification date: 2023-10-18) |
Primary citation | Kesari, P.,Deshmukh, A.,Pahelkar, N.,Suryawanshi, A.B.,Rathore, I.,Mishra, V.,Dupuis, J.H.,Xiao, H.,Gustchina, A.,Abendroth, J.,Labaied, M.,Yada, R.Y.,Wlodawer, A.,Edwards, T.E.,Lorimer, D.D.,Bhaumik, P. Structures of plasmepsin X from Plasmodium falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in mature enzyme. Protein Sci., 31:882-899, 2022 Cited by PubMed: 35048450DOI: 10.1002/pro.4279 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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