7RL8
Crystal Structure of C79A Mutant of Class D beta-lactamase from Clostridium difficile 630
Summary for 7RL8
| Entry DOI | 10.2210/pdb7rl8/pdb |
| Descriptor | Beta-lactamase, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... (4 entities in total) |
| Functional Keywords | structural genomics, center for structural genomics of infectious diseases, csgid, blad, hydrolase |
| Biological source | Clostridioides difficile (Peptoclostridium difficile) |
| Total number of polymer chains | 4 |
| Total formula weight | 117414.35 |
| Authors | Minasov, G.,Shuvalova, L.,Dubrovska, I.,Rosas-Lemus, M.,Jedrzejczak, R.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2021-07-23, release date: 2021-08-11, Last modification date: 2026-02-11) |
| Primary citation | Rosas-Lemus, M.,Dey, S.,Minasov, G.,Tan, K.,Anderson, S.M.,Brunzelle, J.,Nocadello, S.,Shabalin, I.,Filippova, E.,Halavaty, A.,Kim, Y.,Maltseva, N.,Osipiuk, J.,Minor, W.,Joachimiak, A.,Savchenko, A.,Anderson, W.F.,Satchell, K.J.F. A high-throughput structural system biology approach to increase structure representation of proteins from Clostridioides difficile. Microbiol Resour Announc, 12:e0050723-e0050723, 2023 Cited by PubMed Abstract: causes life-threatening gastrointestinal infections. It is a high-risk pathogen due to a lack of effective treatments, antimicrobial resistance, and a poorly conserved genomic core. Herein, we report 30 X-ray structures from a structure genomics pipeline spanning 13 years, representing 10.2% of the X-ray structures for this important pathogen. PubMed: 37747257DOI: 10.1128/MRA.00507-23 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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