7RIX
RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 2
Summary for 7RIX
| Entry DOI | 10.2210/pdb7rix/pdb |
| Descriptor | RNA, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerases I, II, and III subunit RPABC5, ... (16 entities in total) |
| Functional Keywords | rna polymerase ii, elongation complex, polyamide, small molecule, transcription, dna binding protein-dna-rna complex, dna binding protein/dna/rna |
| Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More |
| Total number of polymer chains | 13 |
| Total formula weight | 490121.89 |
| Authors | Oh, J.,Dervan, P.B.,Wang, D. (deposition date: 2021-07-20, release date: 2022-01-12, Last modification date: 2023-10-18) |
| Primary citation | Oh, J.,Jia, T.,Xu, J.,Chong, J.,Dervan, P.B.,Wang, D. RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder. Proc.Natl.Acad.Sci.USA, 119:-, 2022 Cited by PubMed: 35022237DOI: 10.1073/pnas.2114065119 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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