7RCH
Crystal structure of NS1-ED of Vietnam influenza A virus in complex with the p85-beta-iSH2 domain of human PI3K
Summary for 7RCH
Entry DOI | 10.2210/pdb7rch/pdb |
Descriptor | Non-structural protein 1, Phosphatidylinositol 3-kinase regulatory subunit beta (2 entities in total) |
Functional Keywords | vietnam influenza a virus, ns1, pi3k, viral protein |
Biological source | Influenza A virus (A/Viet Nam/1203/2004(H5N1)) More |
Total number of polymer chains | 4 |
Total formula weight | 68025.32 |
Authors | |
Primary citation | Kim, I.,Dubrow, A.,Zuniga, B.,Zhao, B.,Sherer, N.,Bastiray, A.,Li, P.,Cho, J.H. Energy landscape reshaped by strain-specific mutations underlies epistasis in NS1 evolution of influenza A virus. Nat Commun, 13:5775-5775, 2022 Cited by PubMed: 36182933DOI: 10.1038/s41467-022-33554-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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