7R2G
USP15 D1D2 in catalytically-competent state bound to mitoxantrone stack (isoform 2)
Summary for 7R2G
Entry DOI | 10.2210/pdb7r2g/pdb |
Descriptor | Ubiquitin carboxyl-terminal hydrolase 15, ZINC ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | cysteine protease, hydrolase |
Biological source | Homo sapiens |
Total number of polymer chains | 2 |
Total formula weight | 88624.68 |
Authors | Priyanka, A.,Sixma, T.K. (deposition date: 2022-02-04, release date: 2022-06-08, Last modification date: 2024-01-31) |
Primary citation | Priyanka, A.,Tisi, D.,Sixma, T.K. Mitoxantrone stacking does not define the active or inactive state of USP15 catalytic domain. J.Struct.Biol., 214:107862-107862, 2022 Cited by PubMed: 35605756DOI: 10.1016/j.jsb.2022.107862 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.98 Å) |
Structure validation
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