7QTQ

Structure of Native, iodinated bovine thyroglobulin solved on strepavidin affinity grids.

Summary for 7QTQ

Entry DOI	10.2210/pdb7qtq/pdb
EMDB information	14145
Descriptor	Thyroglobulin, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	thyroglobulin, thyroid hormone, iodine, precursor, hormone
Biological source	Bos taurus (cattle)
Total number of polymer chains	2
Total formula weight	612761.51
Authors	Marechal, N.,Weitz, J.C.,Serrano, B.P.,Zhang, X. (deposition date: 2022-01-15, release date: 2022-05-04, Last modification date: 2023-11-15)
Primary citation	Marechal, N.,Serrano, B.P.,Zhang, X.,Weitz, C.J. Formation of thyroid hormone revealed by a cryo-EM structure of native bovine thyroglobulin. Nat Commun, 13:2380-2380, 2022 Cited by PubMed: 35501346 DOI: 10.1038/s41467-022-30082-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation