7QTQ
Structure of Native, iodinated bovine thyroglobulin solved on strepavidin affinity grids.
Functional Information from PROSITE/UniProt
| site_id | PS00484 |
| Number of Residues | 30 |
| Details | THYROGLOBULIN_1_1 Thyroglobulin type-1 repeat signature. YvpqCaed.GsFqtvQcgkdgasc....WCVdad.G |
| Chain | Residue | Details |
| A | TYR48-GLY77 | |
| A | TYR116-GLY145 | |
| A | TYR315-GLY343 | |
| A | PHE615-GLY642 | |
| A | PHE682-GLY709 | |
| A | TYR1027-GLY1056 | |
| A | PHE1104-GLY1132 | |
| A | TYR1165-GLY1195 | |
| A | VAL1469-GLY1470 |
| site_id | PS00941 |
| Number of Residues | 11 |
| Details | CARBOXYLESTERASE_B_2 Carboxylesterases type-B signature 2. EDCLYLNVFvP |
| Chain | Residue | Details |
| A | GLU2279-PRO2289 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 122 |
| Details | Domain: {"description":"Thyroglobulin type-1 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00500","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 134 |
| Details | Domain: {"description":"Thyroglobulin type-1 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00500","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 114 |
| Details | Repeat: {"description":"Type IIIA","evidences":[{"source":"UniProtKB","id":"P01266","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Not glycosylated","evidences":[{"source":"PubMed","id":"8424663","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Iodotyrosine; alternate","evidences":[{"source":"UniProtKB","id":"P01266","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"Iodotyrosine","evidences":[{"source":"UniProtKB","id":"P01266","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Triiodothyronine; alternate","evidences":[{"source":"UniProtKB","id":"P01266","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Thyroxine","evidences":[{"source":"UniProtKB","id":"P01266","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Diiodotyrosine","evidences":[{"source":"UniProtKB","id":"P01266","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 10 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) (hybrid) asparagine; alternate","evidences":[{"source":"PubMed","id":"8424663","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 8 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) (high mannose) asparagine","evidences":[{"source":"PubMed","id":"8424663","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
