7QQH

Crystal structure of MYORG (D520N) in complex with Gal-a1,4-Glc

Summary for 7QQH

• Entry DOI: 10.2210/pdb7qqh/pdb
• Related: 7QQF 7QQG
• Descriptor: Myogenesis-regulating glycosidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: gh31, glycoside hydrolase, myorg, net37, galactosidase, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 297792.27

Authors

Meek, R.W.,Davies, G.J. (deposition date: 2022-01-07, release date: 2022-08-31, Last modification date: 2024-01-31)

• Primary citation: Meek, R.W.,Brockerman, J.,Fordwour, O.B.,Zandberg, W.F.,Davies, G.J.,Vocadlo, D.J.; The primary familial brain calcification-associated protein MYORG is an alpha-galactosidase with restricted substrate specificity.; Plos Biol., 20:e3001764-e3001764, 2022; PubMed: 36129849; DOI: 10.1371/journal.pbio.3001764

Experimental method

X-RAY DIFFRACTION (2.25 Å)