7QQG

Crystal structure of MYORG bound to 1-deoxygalactonojirimycin

7QQG の概要

• エントリーDOI: 10.2210/pdb7qqg/pdb
• 関連するPDBエントリー: 7QQF 7QQH
• 分子名称: Myogenesis-regulating glycosidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: gh31, glycoside hydrolase, myorg, net37, galactosidase, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 296038.74

構造登録者

Meek, R.W.,Davies, G.J. (登録日: 2022-01-07, 公開日: 2022-08-31, 最終更新日: 2024-01-31)

• 主引用文献: Meek, R.W.,Brockerman, J.,Fordwour, O.B.,Zandberg, W.F.,Davies, G.J.,Vocadlo, D.J.; The primary familial brain calcification-associated protein MYORG is an alpha-galactosidase with restricted substrate specificity.; Plos Biol., 20:e3001764-e3001764, 2022; PubMed: 36129849; DOI: 10.1371/journal.pbio.3001764

実験手法

X-RAY DIFFRACTION (2.43 Å)