7QPT

Botulinum neurotoxin A4 cell binding domain in complex with GD1a oligosaccharide

Summary for 7QPT

• Entry DOI: 10.2210/pdb7qpt/pdb
• Descriptor: Neurotoxin type A, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: cell binding domain, receptor, oligosaccharide, neurotoxin, toxin
• Biological source: Clostridium botulinum
• Total number of polymer chains: 2
• Total formula weight: 103510.82

Authors

Gregory, K.S.,Acharya, K.R.,Liu, S.M.,Mojanaga, O.O. (deposition date: 2022-01-05, release date: 2022-03-16, Last modification date: 2024-01-31)

• Primary citation: Gregory, K.S.,Mojanaga, O.O.,Liu, S.M.,Acharya, K.R.; Crystal Structures of Botulinum Neurotoxin Subtypes A4 and A5 Cell Binding Domains in Complex with Receptor Ganglioside.; Toxins, 14:-, 2022; PubMed: 35202156; DOI: 10.3390/toxins14020129

Experimental method

X-RAY DIFFRACTION (2.3 Å)