7QPT

Botulinum neurotoxin A4 cell binding domain in complex with GD1a oligosaccharide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Neurotoxin type A	polymer	433	50756.5	2	UniProt (Q3LRX8) Pfam (PF07953) Pfam (PF07951)	Clostridium botulinum
2	C, D (C, D)	N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose	branched		998.9	2	In PDB GlyTouCan (G03277YI)
3	E, F (A, B)	water	water		18.0	237	Chemie (HOH)

Sequence modifications

A, B: 877 - 1302 (UniProt: Q3LRX8)

PDB	External Database	Details
Met 870	-	initiating methionine
His 871	-	expression tag
His 872	-	expression tag
His 873	-	expression tag
His 874	-	expression tag
His 875	-	expression tag
His 876	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	101513.0
Branched	Number of molecules	2
	Total formula weight	1997.8
All*	Total formula weight	103510.8

*Water molecules are not included.